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Two distinct porcine tissue sources are selected for their specific characteristics and provide the best composition for further refinement.
These two source tissues (which are not small intestinal submucosa or dermis) are protected by trade secrets and are not disclosed to the public.
This source tissue is a
that provides mechanical
This source tissue is an
extracellular matrix ideally
suitable for further refinement.
Based on 165 years of expertise, Geistlich transforms the source tissues into an advanced design with the precise characteristics to support wound healing.
The refinement step is what differentiates Geistlich Derma-Gide® from allografts – which can only be minimally manipulated – and other first generation xenografts.
A pore size of 10–400 µm
is optimized for cell
soaks up 9 times its weight
in fluid and may be applied
onto freshly debrided wounds.
The bi-layered design of Geistlich Derma-Gide® mimics the structural organization of human skin facilitating re-epithelialization and cell ingrowth.
The integrated structure is a result of
the refinement process and the two
layers are mechanically linked to form
a durable and easy to use solution.
The upper compact layer of Geistlich Derma-Gide® mimics the skin’s basement membrane allowing keratinocyte migration as well as growth factor binding and preservation.
The structure of the lower porous layer supports MMP activity modulation and the formation of a physiological extracellular matrix.
It also provides an optimized environment for cell migration, attachment and vascularization.
Ease of Handling
Geistlich Pharma North America Inc.
902 Carnegie Center, Suite 360
Princeton, NJ 08540 USA
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